Increasing number of issues

My hots game has been amassing issues for awhile now and I do not know how to get rid of them (examples below).
Even scan and repair or a complete de- and subsequent re installation does not fix these issues.
Are there maybe some settings that linger even after a re installation that I could manually get rid of in order to get a 100% fresh installation?
Bug examples:

  1. My first login attempt almost always fails, it then defaults to US servers although I only play on EU, sometimes even subsequent logins fail.
  2. I completely disabled clicking on minimap, yet sometimes it still wrongly allows clicking on the minimap.
  3. I cannot add anyone to my friendslist, it always fails, and my list is not full.

The list goes on with some minor inconveniences that are not backbreaking by themselves but keep accumulating and therefore get more annoying by time.
Thanks for any help.