Since the last patch that broke the talent screens, macros with mouseover bound to mouse 4+5 no longer work. This worked before.
This issue is the same from 2020 as described at @Mouseover macro not working with MB4/MB5 - #4 by Maicasfanta-twisting-nether
The same macros work if I use the number keys they share with the mouse buttons, or to other numbers without mouse button binds. But it’s only the mouse clicks that do not work with the mouseovers. The buttons on the same macro work for non-mouseover targets (ie selecting the target to heal/damage etc).