Diablo 3 had this problem too, there’s just way too much crap in the environment to click on. All the little cairns and bags to loot are annoying, distracting, and when you’re in the middle of a fight they are constantly getting in the way of what I’m trying to do. Not to mention the lore objects that are present in some scripted fight areas that you have to drag a battle away from because they’re too easy to click on when you’re trying not to die.
Diablo 2 had a lot of them if you knew where to look but it was also very easy to pass over them without ever knowing they were there. In D4 though you can’t go more than a screen without a bunch of objects to interact with, and I’m not including any of the gathering materials because those are fine on their own.
Please just reduce the amount of crap in the environment to ‘loot.’ I’m here to kill monsters n ish, not constantly scrounge through lost belongings and rocks hiding a pair of blue pants.