Is this possible?

[Elvenbane-kazzak]

@Rasca-blackhand

Mouseover Enemy and target Enemy = Cast Spell on Enemy
Mouseover and target friend or self = cast on friend or self

I want the mouseovers to override both the target enemy and target friend or self.

This is what you want:

@Elvenbane-kazzak

Basic Help/Harm Macro

This will cast one spell when mousing over or targeting a friend and another when mousing over or targeting an enemy.

#showtooltip
/cast [mod:alt,@player] [@mouseover,help,nodead] HELP_SPELL; [@mouseover,harm,nodead] [harm] HARM_SPELL; HELP_SPELL