You might get away without the coma if your toon was in the Ghostlands the last years and haven’t heard a lot about the dragon islands. You just need to know there was a scourge invasion in Ghostlands as well. Other than that, you need to know that Lorthemar and Thalyssra have married.
I think the biggest change is the peace between Alliance and Horde. This will not change until at least 2030 in reallife. You have a lot more neutral opportunities, but less rp-pvp options with the other faction. Depending on what you like, this was a major win or major loss for many guilds on AD.