After starting D3 from launcher I get error code
AE98FA44-4390-45FA-97A6-58F2D52C369F and crashes then reverts to the launcher.
pls help 
I’m having the same issue… If you find a solution let me now pls…
You should first of all try Closing Brackground programs.
Also reinstalling your NVIDIA drivers with a “clean install” which you find in the Custom Install options, may help in this case: GeForce Game Ready Driver | 446.14 | Windows 10 64-bit | NVIDIA
One other thing is you may want to try a different speaker output and not your Bluetooth Headset, it’s possible that could be causing the issue here too.
If the issue persists, please upload your system files to pastebin.com and reply with the links to the files using the preformatted text option to encapsulate the links.
For your issue Goblin28, without more information you may want to check out this topic: Diablo III does not start - #9 by mastershiff-21918