Same for me. I get this whenever I try to complete the quest “Under Thrallmar” and hover over the pickaxe reward. When I unequip my 2-handed weapon, I can hover it safely.
It also happens on a quest item “Smoke Signal” (not sure if its the right translation as Im playing on the german client) when staying under the turrets in outland as alliance trying to mark them.
It acutally happens any single time and is, like other stated, 100% recreateable.
No matter the settings, fresh installs on other hard drives, deleting all addons. Nothing worked so far.