Event ID 4101

So there are a few things we can try for this:

Remove any programs that are using Overlays. Discord, Overwolf, NZXT CAM Fan Control software etc.

Uninstall any graphics accelerator software. Note that this is typically provided by a graphics card company, or will advertise “boost game performance” on it.

Delete the game’s Blizzard App cache folder.

  1. Press the Windows + R keys
  2. In the Run Box type %programdata% and press OK
  3. In the ProgramData folder open the Blizzard Entertainment folders
  4. Delete the game’s folder in the Blizzard Entertainment folder

If you have done the above and still have the issue then I would suggest searching the Nvdia Support site for “TDR Error” or “nvlddmkm stopped”.
They have posts about this in their forums and also on the support section of their site.