A part of the rune quest Wisdom of the guardians is to get cursed and poisoned and cure your self whilst having the buff Duty of the warden.
Mobs who curse/poison are at the level ~40-44 range so as a level 60 their chance of hitting is very low.
QoL change: Add a 100% hit chance for the Gordunni warlock Shrink spell and Zukk’ash wasp poison while buffed with Duty of the warden (ID=446448)
Not necessarily a big deal as sooner or later they will land their attacks, but tagging and holding mobs from others while they’re questing seems like a design flaw.