WoW randomly freezes when tapping back into the game

Checking logs or something in between pulls with Chrome often lets my WoW freeze when tapping back into it. This causes then that WoW needs ~10sec until it catches itself again. I highly doubt that this has anything todo with my PC as the Hardware is pretty up2date. So I assume it is some kind of setting that is not correct. This PC was just built a few days ago so every driver, the OS and so on is up2date as well. As I had the very same issue with my previous PC, maybe some kind of Addon or WeakAura messing around here?

Here is a DxDiag Report for my System: https://pastebin.com/pTVSjH7R

And these are my WoW settings:
Part 1: https://i.imgur.com/oQPgHYp.jpeg
Part 2: https://i.imgur.com/Or95k5I.jpeg
Part 3: https://i.imgur.com/nxbBest.jpeg

These are the AddOns I’m currently using: https://pastebin.com/X4ww9PcX

And these are the WeakAuras currently installed:
Part 1: https://i.imgur.com/uO68af3.jpeg
Part 2: https://i.imgur.com/fF7Vbys.jpeg
Part 3: https://i.imgur.com/F57JfLA.jpeg

Usually I have ~110-120 fps while fighting Bosses like Smolderon Mythic and ~280 fps while in open areas. So I guess the WoW settings should be fine?

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